association between elf and rf electromagnetic field and leukemia

نویسندگان

majid mahdavi department of biology, faculty of natural science, university of tabriz, tabriz, iran.

reza yekta department of biology, faculty of natural science, university of tabriz, tabriz, iran.

saeed hesami tackallou department of biology, garmsar branch, islamic azad university, tehran, iran.

چکیده

extremely low frequency (elf) electromagnetic field (elf-emfs) are widely employed in electrical appliances and different equipment such as television sets, elf-emfs can  affect biological systems by increasing production  ros. the altered balance between ros generation and elimination plays a critical role in a variety of pathologic conditions. ros levels have been observed in several hematopoietic malignancies including acute and chronic myeloid leukemia. elf-emfs exposure significantly decreased nitric oxide synthase (inos) protein expression lower levels of no have been demonstrated to exert a protective function in leukemic and melanoma cells and to inhibit effector caspases by s-nitrosylation. also elf-emfs can decrease melatonin production by effects on n-acetyltransferase. melatonin is an antioxidant, effective in protecting nuclear dna. transmitters emitting radio frequency electromagnetic fields (rf-emfs) are usually not located in populated areas but some epidemiology studies showed association distance transmitters from residential area and leukemia.

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عنوان ژورنال:
journal of paramedical sciences

جلد ۶، شماره ۲، صفحات ۰-۰

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